HKBU's Cross-disciplinary Research on the Neurological Impacts of SARS-CoV-2 Infection and The Entry Mechanism Awarded the RGC's Collaborative Research Fund
An interdisciplinary research project led by Dr Catherine HOR Hong-Huan , Research Assistant Professor from the Department of Chemistry, has recently received a Collaborative Research Fund (CRF) by the Research Grant s Council . CRF is one of the most competitive research grants in Hong Kong that supports multi-investigator, multi-disciplinary projects in order to encourage more research groups to engage in creative and high quality cross-disciplinary projects. As the team leader, Dr Hor leads a team of international scientists with complementary expertise, including virologists, neuroscientists, and synthetic chemist s from HKBU ’s Department of Chemistry, Wuhan Institute of Virology, Duke-NUS Medical School, and National University of Singapore (NUS) to embark on a cross-disciplinary research project. The team is investigating the viral entry mechanism of SARS-CoV-2 in the neurons, and its long-term neuropathological consequences. Given that COVID-19 patients exhibit multiple neurological features, the project is of timely and significant scientific impact. The project shall uncover new insights on the SARS-CoV-2 entry mechanism into neurons, and will offer a better understanding of SARS-CoV-2 pathogenesis in the central nervous system. These findings shall lay the foundation for the development of novel therapeutics tackling SARS-CoV-2 induced neuropathology.